Night train Bruxelles / Brussel – Milano
(ES 456 + 457)

Night train Bruxelles / Brussel – Milano

Take the night train on your next trip to Bruxelles / Brussel or Milano!

Have you ever travelled by night train to Bruxelles / Brussel or Milano? It's probably the most relaxing, fun, and eco-friendly way to get to your destination. The 1107 km long train journey emits approximately 27 times less compared to a flight. Read more on the global warming reduction potential of night trains in our study on the topic.

When travelling with the 456 + 457 train, you can choose between the following categories:

• Normal seats: The cheapest option
• Couchette compartment: Simple, shelf-like beds in a cabin shared by usually 4-6 persons
• Sleeping compartment: Soft beds in a cabin typically shared by 1-3 persons, with a washing basin inside (and in some cases even with a private toilet and shower)

Travel by night train between Belgium, Germany, Switzerland, and Italy – timetable information

Please always verify timetable information with the operator when booking the train, and also prior to your departure.

Belgium to Italy: 456 Bruxelles Midi / Brussel Zuid – Milano Porta Garibaldi

Night train 456 departs from Bruxelles Midi / Brussel Zuid at 17:56, and arrives at Milano Porta Garibaldi at 11:30. It has intermediate stops in Liège Guillemins / Luik Guillemins, Aachen Hbf, Köln Süd, Zürich HB, Arth-Goldau, Göschenen, Bellinzona, Lugano, Chiasso and Como San Giovanni. The total trip duration is 17:34 hours. The train leaves Bruxelles / Brussel every Monday, Thursday and Saturday, but note the following information: From 2026-09-09.

Italy to Belgium: 457 Milano Porta Garibaldi – Bruxelles Midi / Brussel Zuid

The return trip, night train 457, departs from Milano Porta Garibaldi at 17:30, and arrives at Bruxelles Midi / Brussel Zuid at 11:10. It has intermediate stops in Como San Giovanni, Chiasso, Lugano, Bellinzona, Göschenen, Arth-Goldau, Zürich HB, Köln Süd, Aachen Hbf and Liège Guillemins / Luik Guillemins. The total trip duration is 17:40 hours. The train leaves Milano every Wednesday, Friday and Sunday, but note the following information: From 2026-09-10.

Buy tickets for the night train from Bruxelles / Brussel to Milano

This night train line is operated by European Sleeper Cooperatïe and you can book tickets on their official website. We also recommend you read our tips and tricks page for booking international train tickets.

Do you find it too difficult to book night train tickets? Is your favourite line often sold out or are tickets way too expensive? You could think there is little to be done about that – but actually this can be solved politically: By improving conditions for both operators and travellers. Learn more on how we get more night trains in our General Position Paper, or join your local Back on Track group right away.